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Astrocytes in Health                 And Dementia

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London, UK

26th September 2019

The Speakers

Section 01

Basic science of astrocytes in vitro/preclinical

Luc Pellerin

Lausanne University, Switzerland

Anne-Karine Bouzier-Sore

Centre RMSB, France

Sarah Jolly 

 University College London, UK

Eduardo R. Zimmer 

UFRGS, Brazil

Section 02

Radiochemistry/design, translation, preclinical and human

Salvatore Bongarzone

King’s College London, UK

Diana Cash

King’s College London, UK

Igor Fontana

UFRGS, Brazil/King’s College London, UK

Section 03

In vivo astrocyte biomarkers

Nick Ashton

Gothenburg University, Sweden

Elena Rodriguez Vieitez

Karolinska Institute, Sweden

Christine Parker

 GSK/Imperial College London

Paul Edison

Imperial College London, UK

 

Programme

26th September

3 sessions; ~15min talks with open discussion/questions after each

08:30 – 09:00  |  Registration

09:00 – 09:15  |  Intro, thank sponsor(s), housekeeping etc

 

09:15 – 10:45 

Section 1 – Basic science of astrocytes in vitro/preclinical

 

Luc Pellerin |  Lausanne University, Switzerland 

Astrocytes as activity-dependent lactate suppliers for neurons: Key role for MCT4

Anne-Karine Bouzier-Sore  |  Centre RMSB, France

Importance of astrocytic lactate in brain metabolism: from functional brain imaging to neuroprotection

Sarah Jolly  |  University College London, UK

Targeting astrocytes in neurodegenerative diseases: from basic science to drug discovery

Eduardo R. Zimmer  |  UFRGS, Brazil

Astrocyte glutamate transport drives [¹⁸F]FDG-PET signal

10:45 – 11:15  |  Coffee break

 

11:15 – 12:15

Section 2 – Radiochemistry/design, translation, preclinical and human

Salvatore Bongarzone  |  King’s College London, UK

What we need to know to design a CNS PET radiotracer

Diana Cash  |  King’s College London, UK

Preclinical imaging and neuroinflammatory biomarkers

 

Igor Fontana  |  UFRGS, Brazil/King’s College London, UK  

Development of Carbon-11 PET Pro-Radiotracer for Imaging the Astroglial Excitatory Amino Acid Transporter

12:15 – 13:15  |  Lunch - Buffet provided

13:15 – 14:45 

Section 3 – In vivo astrocyte biomarkers

Nick Ashton  |  Gothenburg University, Sweden

The current status of fluid biomarkers in Alzheimer's disease and related disorders.

 

Elena Rodriguez Vieitez  |  Karolinska Institute, Sweden

PET imaging of astrocytosis using [¹¹C]-deuterium-L-deprenyl in translational and multimodal studies

 

Christine Parker  |  GSK/Imperial College London, UK

Development of a PET Ligand Targeting the Imidazoline-I2 Binding site – a potential astrocytic marker?

 

Paul Edison  |  Imperial College London, UK

Evaluation of astroglial activation using novel [11C]-BU99008 PET

14:45 – 15:15  |  Tea

 

15:15 – 16:30  |  “Open Mic” &/or group discussions to promote collaboration

 

16:30 – 17:00  |  Wrap-up/final discussion

The Venue

St Thomas' Hospital

4th floor Lambeth wing.

Westminster bridge road, SE17EH

London, UK

 
 

01

11

50

DAY
SPEAKERS
PARTICIPANTS

Acknowledgment

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